All comics
- Massive Pwnage
- Massive Sqwertz
- Masters of the Art
- Mastorism
- Material Components
- Mathema
- Matriculated
- Matter of Fact
- Matul Remrit
- Maverick and "Friends"
- maximumble
- Max Overacts
- Max vs. Max
- Maxwell the Demon
- MAYA
- Maybe Too Metal
- Mayonaka Densha
- The Mazosi Gems
- McDuffies
- Meago saga
- Meaningless Comics
- Meat and Bone
- MeatShield
- Meaty Yogurt
- Mechagical Girl Lisa A.N.T
- MechaSentient
- MediocreComic
- Meditations
- Medium Large
- The Meek
- Meen Comics
- MegaCynics
- megaGAMERZ 3133T
- Mega Maid and Chop Chop Princess
- Mega New York
- Megan Kearney's Beauty and The Beast
- Megatokyo
- Meiosis
- Melaines Choles
- Melissa and Marshy
- Mellapants
- Melonpool
- Memento Mori
- Memento Mori
- Memento Mori
- Memento Vivere
- Memesink
- Memil
- Memoria
- Ménage à 3
- Men In Hats
- Mensch unserer Zeit
- Meraki
- Merceneiress
- MercWorks
- Mere Happenings in the history of my body
- Mermaid Hostel
- messenger
- Metacarpolis
- Metalero
- Metalero (Spanish)
- Metanoia
- Metaphysical Neuroma
- Metasearch
- Metroid: Third Derivative
- Metro-Jack
- Metrophor
- mezzacotta
- M.F.K.
- Miamaska
- Michael Keaton
- Michael's Exciting Life
- Micro and Macro
- Mid-Evil
- Midnight Macabre
- The Midnight Tea Party
- The Mighty Jambo
- The Mighty Offenders
- The Mighty Power Soul B
- The Mighty Valiants