All comics
- Strange Happenings
- Strange Investigations
- strangekith
- Strange Quark
- Strange Someone
- Strange times
- Strawberry Death Cake
- Stray Crayons
- Strays
- The Streets of San Diablo
- Streta
- Stridspartners
- String Theory
- Striped Socks
- Stripfield (en)
- Stripped Again
- Stripped Comics
- Striptease
- Stripy Six
- Strong Female Protagonist
- Stryders
- Stubble
- The Studio
- Studio Sketchy
- Stud Kickass
- Studs Up
- Stuff of Legends
- Stupid and Insane Defenders Against Chaos
- StupidFox
- Stupidity At Its Finest
- Stupidity in Magic
- Stupidity in the Right Ear
- Stupid Snake
- Stuporheroes
- SubCulture
- Subculture shock
- Subnormality
- Substitute Class Imago
- Subterforge
- Subterfuge
- The Suburban Jungle
- Suburban Tribe
- Succubus Justice
- Such Rubbish
- Sucker Punch to My Emotions
- Sudden Valley
- Sugar Bits
- Sugarstars
- Sugary Serials
- Suicide for hire
- The Suits
- The Summer of Blake Sinclair
- Sunday Morning Coffee
- The Sundays
- Sundays at 10
- Sunday Smash
- Sun Ev-1
- Sunflower Girl
- Sunny Girl
- Sunset Grill
- Supafine
- Supercrash!
- Supercrash! (French)
- Super Doomed Planet Comics
- SuperFogeys
- Super Frat
- SuperFreaks
- The Super-Gay Adventures of Ross Boston
- SuperLavanderia
- Supermahou
- Supermassive Black Hole A*
- Super Mega
- Supernatural Law
- Supernormal Step
- Supernovas
- Superosity
- Super-Peers
- Super Seed
- Super Stick Man
- Super Stupor